1379 Immune Checkpoint Inhibitor-Induced Acute Pancreatitis and Colitis
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چکیده
منابع مشابه
Familial hypertriglyceridemia-induced acute necrotizing pancreatitis: A case report
Acutepancreatitis can infrequently be a life-threatening complication of hypertriglyceridemia. Rarely, hypertriglyceridemia can originate from an inborn genetic error in lipoproteins metabolism. This condition can be manifested by very high serum triglyceride levels (>1000 mg/dl) and a more severe and lethal form of pancreatitis. Here, we present a case of acute pancreatic which was found out t...
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Treatment of acute pancreatitis remains a challenge, with therapy focused on supportive care and treating the inciting etiology. Tumor necrosis factor-alpha (TNFα) inhibitors have shown promising results treating acute pancreatitis in animal models, but they have not been evaluated in human trials yet. A 25-year-old woman presented with ulcerative colitis. She was unresponsive to immunomodulato...
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Acute pancreatitis (AP) Acute pancreatitis (AP) is one of the most common gastrointestinal causes for hospital admission. AP can develop in response to various factors e.g., gallstones, excessive alcohol consumption, viral infections, as well as strong reactions to certain medications. Initiating events for the acinar cell injury take place locally. Premature enzyme activation and abnormal exoc...
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Checkpoint inhibitors are immune-stimulatory antibodies that have transformed the management and prognosis of individuals with metastatic melanoma and other cancers. Checkpoint inhibitor-induced colitis is an increasingly recognized immune-related adverse event that shares many of the same phenotypical, serological, and histological characteristics of both Crohn's disease and ulcerative colitis...
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ژورنال
عنوان ژورنال: American Journal of Gastroenterology
سال: 2019
ISSN: 0002-9270,1572-0241
DOI: 10.14309/01.ajg.0000595044.94402.db